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Slack / Private Message Drop, p.567 [SLACK_000781] · slack_pm:msg:05917

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You know, no point in having data get in the way of a good story.

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A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2021-03-04 12:59 Kristian G. Andersen open

Yeah, junk. "The VOCs have a lot of mutations so they must be recombinants"....
2021-03-04 13:25 Kristian G. Andersen open

*Key* paper from South Africa here - people infected with B.1.351 fully neutralize B.1.351 viruses AND neutralizenon-B.1.351 viruses pretty well. https://www.medrxiv.org/content/10.1101/2021.01.26.21250224v2
2021-03-04 13:27 Kristian G. Andersen open

Also, one very interesting finding - although it's n=1. They had somebody infected by non-B.1.351 _but_ with a virus that had the E484K mutation. The serum from that patient absolutely knocked it out of the park when it came to neuttiers against both B.1.351 and non-B.1.351 - so much so, they had to exclude the individual from most analyses. Ifthis holds up, we might have a winner for near-perfect vaccine antigen - spike + E484K, 2P, and dFCS. That'd becool.
2021-03-04 14:19 Edward C. Holmes open

I finally looked at this carefully. Did you see the BEAST analysis? TempEST found no temporal structure so they went ahead and used a strick clock anyway. On a 440 nt region. [shared file(s): Latrinne.NatComm20.pdf]
2021-03-04 15:13 Kristian G. Andersen

You know, no point in having data get in the way of a good story.