Chat message

Slack / Private Message Drop, p.555 [SLACK_000769] · slack_pm:msg:05789

Date: 2021-02-28 12:58
Type: chat message · slack
recipient: Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker: Andrew Rambaut

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That was the only homoplasy but she had a convincing looking plot of the two 'parents' and the 'recombinant' and itshowed a tract in spike that looked like B.1.1.7 compared to the other parent. But it was actually also the same asthe reference and the other parent had had some mutations. Just so dumb

In context

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2021-02-28 12:54 Andrew Rambaut open

Basically she found a 'californian' virus with 69/70 deletion in it and was claiming it was recombinant with a B.1.1.7.But 69/70 comes up all the time.
2021-02-28 12:54 Andrew Rambaut open

I spent way too long on it.
2021-02-28 12:55 Kristian G. Andersen open

Wait, she specifically said 69/70 came from B.1.1.7 and hence it must be a recombinant? That's, well, dumb. Very.
2021-02-28 12:56 Edward C. Holmes open

What an idiot. I look forward to reviewing that for Cell.
2021-02-28 12:58 Andrew Rambaut

That was the only homoplasy but she had a convincing looking plot of the two 'parents' and the 'recombinant' and itshowed a tract in spike that looked like B.1.1.7 compared to the other parent. But it was actually also the same asthe reference and the other parent had had some mutations. Just so dumb
2021-02-28 12:59 Andrew Rambaut open

The worse thing is we started the meeting with an explanation from Bette about how you detect recombination in viruses.
2021-02-28 13:00 Kristian G. Andersen open

Hahahaha, must have been so painful to go through that.
2021-02-28 13:52 Edward C. Holmes open

She's so awful. I really hope she gets a bit of public ridicule for this.

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