COVID-19 Records

Chat message

Slack / Private Message Drop, p.542 [SLACK_000756] · slack_pm:msg:05647

Page text: p.542 · original PDF

Date
2021-02-23 00:25
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker
Edward C. Holmes

Recipients on this medium are inferred from channel membership, not per-message addressing.

Ha. So that parallels P681H in B.1.1.7?

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

  1. 2021-02-23 00:05 Andrew Rambaut open
    Also I have had some backtracking about the P323L coming up in monkeys - data looks dodgy apparently.
  2. 2021-02-23 00:07 Andrew Rambaut open
    A.23.1 also has a cluster in the UK with E484K
  3. 2021-02-23 00:10 Edward C. Holmes open
    Fascinating. So, D614G or Q613H (and perhaps linked mutations) push the virus down a particular evolutionary 'corridor' which then means that only certain subsequent mutations will follow?
  4. 2021-02-23 00:18 Andrew Rambaut open
    Interestingly it seems that P681R arose after Q613H: [shared file(s): A.23.1_2021-02-02.tree.png]
  5. 2021-02-23 00:25 Edward C. Holmes
    Ha. So that parallels P681H in B.1.1.7?
  6. 2021-02-23 00:41 Edward C. Holmes open
    Reminds me of this: https://science.sciencemag.org/content/328/5983/1272

Full conversation →