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Slack / Private Message Drop, p.462 [SLACK_000676] · slack_pm:msg:04794

Page text: p.462 · original PDF

Date
2021-01-29 12:45
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker
Edward C. Holmes

Recipients on this medium are inferred from channel membership, not per-message addressing.

Yes, a replicatory advantage of B.1.1.7 over B.1.351 would be bloody useful!

In context

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  1. 2021-01-29 12:36 Edward C. Holmes open
    What's he gone and done now?
  2. 2021-01-29 12:37 Kristian G. Andersen open
    Just another talk to scare the shit out of people. I do it pretty well these days (scare the shit out of people - not the talk part). To be aired in 2022.
  3. 2021-01-29 12:43 Edward C. Holmes open
    It was actually really interesting watching the Novavax chat yesterday: basically a 50/50 split on those who thought the results were good/bad.
  4. 2021-01-29 12:43 Robert F. Garry open
    So I agree that B117 will come to dominate quickly. BUT what if B.1.351 comes into play? Will both circulate, will one replace the other? I'm kinda "rooting" for B117.
  5. 2021-01-29 12:45 Edward C. Holmes
    Yes, a replicatory advantage of B.1.1.7 over B.1.351 would be bloody useful!
  6. 2021-01-29 12:46 Kristian G. Andersen open
    The Novavax is a fucking wakeup call like no other - the lack of urgency is disturbing. I don't think most people understand exactly how problematic that is - including vaccine makers and immunologists. "We want perfect data first!". Nope. Fucking move!
  7. 2021-01-29 12:46 Kristian G. Andersen open
    I'm pretty certain B117 will win out first, but as immunity builds up, probably some of these other lineages - OR B117will simply pick up those mutations and continue to dominate. Will be very interesting to watch (and, of course,linages X, Y, Z coming down the pipe....)
  8. 2021-01-29 12:48 Edward C. Holmes open
    Definitely more lineages coming to a place near you soon. It was striking that people just seemed to want to hear the'89%' good news from the Novavax UK trial and not think about the SA data.
  9. 2021-01-29 12:49 Robert F. Garry open
    Yes indeed Eddie - it's distressing. J and J efficacy starting off lower than Novavax.

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