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Slack / Private Message Drop, p.414 [SLACK_000628] · slack_pm:msg:04288

Page text: p.414 · original PDF

Date
2021-01-18 07:20
Type
chat message · slack
recipient
Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker
Kristian G. Andersen

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Now I'm getting concerned. [shared file(s): Image from iOS.jpg]

In context

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  1. 2021-01-18 07:15 Kristian G. Andersen open
    Definitely too early with L452R and I'm annoyed that they put out a press release with no data and before we could actually get a close look at what's going on.The concern I have is that they mentioned this was found in three skilled nursing facility outbreaks with 100% attack rates - if true, then absolutely concerning, but I don't know how good the data is. I should know tomorrow.To the UK variant - this is not great... https://twitter.com/guptar_lab/status/1351181784776634370?s=21
  2. 2021-01-18 07:20 Kristian G. Andersen
    Now I'm getting concerned. [shared file(s): Image from iOS.jpg]
  3. 2021-01-18 07:44 Robert F. Garry open
    Actually the Gupta data fell about where I expected. 3-6 fold reduction is not fantastic for B117, but actually could have been worse. EeeK will likely result in a bigger drop I suspect.
  4. 2021-01-18 08:00 Kristian G. Andersen open
    Yeah, I agree Bob. - right where you might expect it to land. Quite a number of folks with no neuts to either virus aswell. Eeek will for sure be worse and cross the 4x threshold (I believe) is being used in the flu field to trigger avaccine update.
  5. 2021-01-18 08:14 Robert F. Garry open
    That's a good analogy to flu - and you're right vaccine update will be needed. Just hoping that most humans can mount a good response to K484.
  6. 2021-01-18 08:15 Andrew Rambaut open
    Eek + Pooh: ```Accession ID Collection date Submission date Location EPI_ISL_778908 2020-11-30 2021-01-07 North America / USA / Maryland EPI_ISL_791414 2020-11-21 2021-01-08 North America / USA / Maryland EPI_ISL_791426 2020-12-30 2021-01-08 North America / USA / Maryland EPI_ISL_791427 2021-01-01 2021-01-08 North America / USA / Maryland```

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