Slack / Private Message Drop — page 414

[2021-01-17 19:19:22] [Robert Garry] They pretty much nailed the conclusions: "Urgent studies are necessary to determine whether reinfection with newly emerging lineages harboring the mutation S:E484K is a widespread phenomenon or is limited to a few sporadic cases. It will also be crucial to understand the extent to which reinfection contributes to the forward transmission of SARS-CoV-2 in previously exposed populations and the rising number of SARS-CoV-2 cases observed in Amazonas and other Brazilian states during December 2020 - January 2021." [2021-01-17 21:08:20] [Kristian Andersen] I had nothing to do with that press release... just saying. [2021-01-17 21:19:42] [Eddie Holmes] I enjoyed this one Kristian - I like 'The Godfather' puppet hands: [shared file(s): Er8lx6aXAAArjog.jpg] [2021-01-17 21:41:32] [Kristian Andersen] Yeah, the hand is a really nice touch. I assume we fall in the "enables" category? [2021-01-17 21:48:20] [Eddie Holmes] We do. We are being controlled. I think 'chilling accusations' should be a subheading in PO2. [2021-01-18 01:04:46] [Andrew Rambaut] OK - L452R - what do we think? Just chasing variants? https://twitter.com/cychiu98/status/1350985418628587520?s=20 [2021-01-18 01:18:32] [Eddie Holmes] On the watch list but no more at this point [2021-01-18 01:50:49] [Robert Garry] Yes, hand is very good - maybe Alina can borrow it for her next wall of crazy/WSJ article. "I assume we fall in the "enables" category?" Maybe more like super-elite? Both? Dunno. Have to say that "monitoring mutation areas for projected lethality" does describe the coming virological post pretty well. [2021-01-18 04:20:23] [Robert Garry] I'm pretty sure L452R is no LuthoR or LucifeR. I suppose it could be a LesteR. [2021-01-18 07:15:52] [Kristian Andersen] Definitely too early with L452R and I'm annoyed that they put out a press release with no data and before we could actually get a close look at what's going on. The concern I have is that they mentioned this was found in three skilled nursing facility outbreaks with 100% attack rates - if true, then absolutely concerning, but I don't know how good the data is. I should know tomorrow. To the UK variant - this is not great... https://twitter.com/guptar_lab/status/1351181784776634370?s=21 [2021-01-18 07:20:39] [Kristian Andersen] Now I'm getting concerned. [shared file(s): Image from iOS.jpg]