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Slack / Private Message Drop, p.412 [SLACK_000626] · slack_pm:msg:04256

Page text: p.412 · original PDF

Date
2021-01-16 15:20
Type
chat message · slack
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry
Topics
Furin cleavage site and molecular features

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But, the more I look at RmYN02 and RaTG13 s1/s2 cleavage sites the more I'm convinced that there's a bat CoV out there with at least a very close homolg to SARS FCS already there. QTQTNS plus NSPAAR. Put'em together and what'a you got?

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  1. 2021-01-16 15:07 Edward C. Holmes open
    Of course not, but it's not about convincing them - it's about producing the most complete scientific picture possible.
  2. 2021-01-16 15:09 Edward C. Holmes open
    He forgot 'scientific reasons'.
  3. 2021-01-16 15:10 Kristian G. Andersen open
    Hah
  4. 2021-01-16 15:12 Robert F. Garry open
    Not surprising ME a wannabe politician [briefly ran for Senate] and likely pissed of that Biden picked EL for the WHpost.
  5. 2021-01-16 15:20 Robert F. Garry
    But, the more I look at RmYN02 and RaTG13 s1/s2 cleavage sites the more I'm convinced that there's a bat CoV out there with at least a very close homolg to SARS FCS already there. QTQTNS plus NSPAAR. Put'em together and what'a you got?
  6. 2021-01-16 15:40 Robert F. Garry open
    I do keep messing with this. [shared file(s): image.png]
  7. 2021-01-16 15:41 Edward C. Holmes open
    You should get a job at the WIV Bob.
  8. 2021-01-16 15:44 Robert F. Garry open
    I'm told they love me (us) over there.
  9. 2021-01-16 16:10 Edward C. Holmes open
    Hi Bob, I've gone over the Google Docs text and it looks good! The only that I don't quite follow is the logic thecomparisons to RmYN02 as I don't see this virus as being 'ancestral' or falling particularly deep in the phylogeny.We could probably determine the ancestral sequence for all these positions but it will take a bit of work.

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