Chat message

Slack / Private Message Drop, p.412 [SLACK_000626] · slack_pm:msg:04260

Date: 2021-01-16 16:10
Type: chat message · slack
recipient: Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker: Edward C. Holmes

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Hi Bob, I've gone over the Google Docs text and it looks good! The only that I don't quite follow is the logic thecomparisons to RmYN02 as I don't see this virus as being 'ancestral' or falling particularly deep in the phylogeny.We could probably determine the ancestral sequence for all these positions but it will take a bit of work.

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2021-01-16 15:20 Robert F. Garry open

But, the more I look at RmYN02 and RaTG13 s1/s2 cleavage sites the more I'm convinced that there's a bat CoV out there with at least a very close homolg to SARS FCS already there. QTQTNS plus NSPAAR. Put'em together and what'a you got?
2021-01-16 15:40 Robert F. Garry open

I do keep messing with this. [shared file(s): image.png]
2021-01-16 15:41 Edward C. Holmes open

You should get a job at the WIV Bob.
2021-01-16 15:44 Robert F. Garry open

I'm told they love me (us) over there.
2021-01-16 16:10 Edward C. Holmes

Hi Bob, I've gone over the Google Docs text and it looks good! The only that I don't quite follow is the logic thecomparisons to RmYN02 as I don't see this virus as being 'ancestral' or falling particularly deep in the phylogeny.We could probably determine the ancestral sequence for all these positions but it will take a bit of work.

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