Chat message

Slack / Private Message Drop, p.378 [SLACK_000592] · slack_pm:msg:03931

Date: 2021-01-10 16:58
Type: chat message · slack
mentioned: Kristian G. Andersen
recipient: Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker: Robert F. Garry

Recipients on this medium are inferred from channel membership, not per-message addressing.

@Kristian Andersen I am now starting to think that the delayed dosing is vastly inferior to going with a half or one third dose followed by a second half or third dose.

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2021-01-10 16:10 Andrew Rambaut open

So that is what the Manaus experiment will be about. Did 501Y, 484K and 417T appear in combination because it isreinfecting people.
2021-01-10 16:10 Kristian G. Andersen open

Yeah - Manaus (and Israel) will be really really important.
2021-01-10 16:15 Kristian G. Andersen open

If we start seeing reinfections (or vaccine failures) in Manaus / Israel driven by escape, then we might have torethink our entire vaccination strategy. Stockpiling enough supply to vaccinate most of the population while (massively) driving down infections via NPIs - then go out and vaccinate as many people as possible as quickly aspossible.I don't think humans have the ability to do that. In fact, I'm getting increasingly pessimistic that we have the ability toeven control the first few years of the "Reign of COVID-19". I'm seeing too many indicators currently that are makingme very uncomfortable.
2021-01-10 16:17 Kristian G. Andersen open

(coupled with too much wishful thinking - we so desperately yearn for positive news that we forget that things don't just automatically get better).
2021-01-10 16:58 Robert F. Garry

@Kristian Andersen I am now starting to think that the delayed dosing is vastly inferior to going with a half or one third dose followed by a second half or third dose.

Full conversation →