Chat message

Slack / Private Message Drop, p.345 [SLACK_000559] · slack_pm:msg:03630

Date: 2020-12-28 14:50
Type: chat message · slack
recipient: Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker: Edward C. Holmes
Topics: Furin cleavage site and molecular features

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I don't have the sequence for that Cambodian virus and I'll see I can get hold of the key bits of the spike protein. Iwas told it was 'quite divergent'.

Extracted statements

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Statement	Grade	Attribution	Stance
I don't have the sequence for that Cambodian virus and I'll see I can get hold of the key bits of the spike protein.	own voice, substantive	speaker_own	asserts

Statement

Grade

Attribution

Stance

I don't have the sequence for that Cambodian virus and I'll see I can get hold of the key bits of the spike protein.

own voice, substantive

speaker_own

asserts

In context

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2020-12-28 14:41 Edward C. Holmes open

Tigers keep getting infected. Very interesting.
2020-12-28 14:44 Edward C. Holmes open

And here is a new data point for your consumption only - that Cambodian bat virus that mentioned in that Nature news piece without any info...closer than I expected: [shared file(s): data_fullgenome_aligned.fas.tree.pdf]
2020-12-28 14:46 Edward C. Holmes open

Bob - I was also involved in a cat study: [shared file(s): A household case evidences shorter shedding of SARS CoV2 in naturally infected cats compared to their human owners.pdf]
2020-12-28 14:46 Robert F. Garry open

Indeed - several zoos and various cats including leopards and lions.
2020-12-28 14:50 Edward C. Holmes

I don't have the sequence for that Cambodian virus and I'll see I can get hold of the key bits of the spike protein. Iwas told it was 'quite divergent'.
2020-12-28 14:50 Robert F. Garry open

@Eddie Holmes Oh that's very interesting! Will be interested to see Spike.
2020-12-28 14:53 Edward C. Holmes open

@Eddie Holmes I'll see what I can do...complex politics.
2020-12-28 14:56 Robert F. Garry open

Thanks Eddie - @Kristian Andersen It suddenly occurs to me that the monkey passaged virus data might be interesting - weren't there changes in the spike?
2020-12-28 15:14 Robert F. Garry open

The cats are very interesting as previously discussed here. Surely seems like they are getting infected pretty easily.In the zoos the cats are probably getting infected by the airborne route. People coughing and breathing into open cages? I suppose that the zookeepers could infecting them somehow, but there are not too many instances ofpeople and these big cats together in very close quarters except under very controlled conditions [like a vet doing anexam]. As for origins, it does put a heavy spotlight back on the Feliforms.

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