Slack / Private Message Drop — page 345

[2020-12-28 14:44:55] [Eddie Holmes] [thread - ID: 2020-12-28 14:44:55] And here is a new data point for your consumption only - that Cambodian bat virus that mentioned in that Nature news piece without any info...closer than I expected: [shared file(s): data_fullgenome_aligned.fas.tree.pdf] [2020-12-28 14:46:22] [Eddie Holmes] Bob - I was also involved in a cat study: [shared file(s): A household case evidences shorter shedding of SARS CoV 2 in naturally infected cats compared to their human owners.pdf] [2020-12-28 14:46:40] [Robert Garry] Indeed - several zoos and various cats including leopards and lions. [2020-12-28 14:50:27] [Eddie Holmes] I don't have the sequence for that Cambodian virus and I'll see I can get hold of the key bits of the spike protein. I was told it was 'quite divergent'. [2020-12-28 14:50:52] [Robert Garry] [thread - ID: 2020-12-28 14:44:55] @Eddie Holmes Oh that's very interesting! Will be interested to see Spike. [2020-12-28 14:53:13] [Eddie Holmes] [thread - ID: 2020-12-28 14:44:55] @Eddie Holmes I'll see what I can do...complex politics. [2020-12-28 14:56:22] [Robert Garry] Thanks Eddie - @Kristian Andersen It suddenly occurs to me that the monkey passaged virus data might be interesting - weren't there changes in the spike? [2020-12-28 15:14:52] [Robert Garry] The cats are very interesting as previously discussed here. Surely seems like they are getting infected pretty easily. In the zoos the cats are probably getting infected by the airborne route. People coughing and breathing into open cages? I suppose that the zookeepers could infecting them somehow, but there are not too many instances of people and these big cats together in very close quarters except under very controlled conditions [like a vet doing an exam]. As for origins, it does put a heavy spotlight back on the Feliforms. [2020-12-28 16:00:53] [Eddie Holmes] If it is moving around zoos in an airborne manner then the infections in felids are even more striking as you would expect supposedly high risk animals like great apes also to be infected. Yet, it is consistently not apes and consistently is tigers. [2020-12-28 16:41:57] [Kristian Andersen] [thread - ID: 2020-12-28 14:44:55] @Eddie Holmes That _*is*_ close - interesting.... [2020-12-28 16:43:14]