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Slack / Private Message Drop, p.336 [SLACK_000550] · slack_pm:msg:03532

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(most 501Y from Wales are this lineage at the moment but it is changing)

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A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2020-12-21 14:30 Andrew Rambaut open

Very confusingly (and coincidentally) it is lineage B.1.1.70
2020-12-21 14:30 Andrew Rambaut open

Here are all the mutations from Wuhan: Spike D614G, Spike N501Y, N G204R, N Q9H, N R203K, NS3 Y156C, NS7a T14I, NSP3 H1539Y, NSP3 S126L, NSP5 G71S, NSP5 P132L, NSP12 P323L, NSP15 A217V, NSP15 M271I, NSP15 T33I
2020-12-21 14:30 Andrew Rambaut open

EPI_ISL_710967
2020-12-21 14:30 Kristian G. Andersen open

Awesome - thanks
2020-12-21 14:31 Andrew Rambaut

(most 501Y from Wales are this lineage at the moment but it is changing)
2020-12-21 14:31 Andrew Rambaut open

So no other spikes apart from 614G but everyone has one of those these days
2020-12-21 14:36 Kristian G. Andersen open

That's interesting about the Wales lineage - so if that's really spreading fast too and we believe there's a causalrelationship, then it's down to N501Y - potentially with D614G, but as you say, they all have that one (including that earlier cluster in Australia that didn't go anywhere).
2020-12-21 14:42 Robert F. Garry open

guess not - color blind
2020-12-21 14:57 Andrew Rambaut open

My feeling is the Welsh cluster isn't growing at the same rate. It is at least as old but hasn't taken over or spread toother places. Also may have been amplified by some hospital outbreaks.