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Slack / Private Message Drop, p.335 [SLACK_000549] · slack_pm:msg:03521

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That E484K gotta be making some major differences in the structure

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A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2020-12-21 14:09 Kristian G. Andersen open

Heh. Oooookay.
2020-12-21 14:09 Kristian G. Andersen open

2/3 mutations associated with rodents?
2020-12-21 14:11 Kristian G. Andersen open

Yeah, so SA is K417N and N501Y - SA/UK both Q493
2020-12-21 14:12 Kristian G. Andersen open

So really major amino acid changes in the few they have - flipping around charges, etc.
2020-12-21 14:13 Kristian G. Andersen

That E484K gotta be making some major differences in the structure
2020-12-21 14:19 Robert F. Garry open

Going full in: the FCS of some strains of mouse hepatitis virus is *H*RARRS.
2020-12-21 14:23 Kristian G. Andersen open

There you go. It's time we go back to Andrew's London sewage theory.
2020-12-21 14:26 Kristian G. Andersen open

@Andrew Rambaut - do you have a good reference for the best "Wales" lineages?
2020-12-21 14:26 Andrew Rambaut open

You mean what muts it has?