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Slack / Private Message Drop, p.318 [SLACK_000532] · slack_pm:msg:03342

Date: 2020-12-16 04:12
Type: chat message · slack
recipient: Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker: Robert F. Garry

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If the change in the FCS makes it somehow better able to infect the upper airways this could impact spread. Mightbe reflected in lower Ct values in nasal swabs.

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2020-12-16 04:12 Robert F. Garry

If the change in the FCS makes it somehow better able to infect the upper airways this could impact spread. Mightbe reflected in lower Ct values in nasal swabs.
2020-12-16 04:33 Robert F. Garry open

Doug's (D614G) daughter Nancy (N501Y) is certainly interesting - the deletion in the NTD along with the change near/in the RBD plus the rare FCS mutation are very likely driving some phenotype.
2020-12-16 04:41 Andrew Rambaut open

Yes - I am really convinced it is spreading because of these mutations not despite. And I am usually very cautious. Iam keeping my eye on a lineage with N501Y and none of the other mutations that is also spreading in the UK.

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