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Slack / Private Message Drop, p.293 [SLACK_000507] · slack_pm:msg:03055

Page text: p.293 · original PDF

Date
2020-12-04 09:18
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker
Andrew Rambaut
Topics
Vaccines

Recipients on this medium are inferred from channel membership, not per-message addressing.

But the RNA vaccines may recombine with your viruses and integrate into your genome and all sorts of things.

Extracted statements

Rule-extracted, not adjudicated. The grade says what may be done with each one; read the document above before relying on any of them.

StatementGradeAttributionStance
But the RNA vaccines may recombine with your viruses and integrate into your genome and all sorts of things. own voice, substantive speaker_own asserts

In context

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  1. 2020-12-04 07:49 Robert F. Garry open
    https://www.usatoday.com/story/news/health/2020/12/04/vaccine-ethics-does-continuing-covid-19-trials-put-volunteers-risk/6473436002/ This was one reason I advocated for human challenge trials - those in the placebo arm remain "sitting ducks."
  2. 2020-12-04 08:28 Andrew Rambaut open
    The Wellcome Trust is funding a challenge trial. They have manufactured the virus. I don't which vaccines they intend to use.
  3. 2020-12-04 09:12 Robert F. Garry open
    GOOD! A major question that randomized "wild" trials will struggle to answer is whether vaccinees still produce enough virus to remain infectious if exposed. Contrary to what I thought would be the case we found at Tulane that virus load had very little impact on whether or not a student was a "spreader." There was not complete sterilizingimmunity in the NHP challenge trials AFAIK. So, you could have a situation where vaccinees are protected against serious disease, but are still able to transmit the virus to some degree.
  4. 2020-12-04 09:17 Kristian G. Andersen open
    Damn IgA vs IgG! As for sterilizing immunity - the animal trials for both the J&J and RNA vaccines were promising on this aspect -the Oxford vaccine, not at all.
  5. 2020-12-04 09:18 Andrew Rambaut
    But the RNA vaccines may recombine with your viruses and integrate into your genome and all sorts of things.
  6. 2020-12-04 09:20 Kristian G. Andersen open
    ... and lead to sterilization. Which may not be a bad thing.

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