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Slack / Private Message Drop, p.10 [SLACK_000224] · slack_pm:msg:00091

Date: 2020-05-04 17:13
Type: chat message · slack
recipient: Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker: Robert F. Garry

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Drosten sorta comes out and says it too. "The emergence of HCoV-OC43 in humans was proposed to be linked to a host-switching event around the year 1890, a time that coincides with a pandemic of respiratory disease recorded inhumans (Vijgen et al., 2005, 2006)."

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2020-05-04 16:54 Robert F. Garry open

Yes - but the article also says that OC43 caused the 1898 Russian flu. I thought it was H3N8. Is this true aboutOC43 or don't we know. OC43 has a furin site and O-glycans.
2020-05-04 16:56 Edward C. Holmes open

There can't be any evidence it is OC43, surely?
2020-05-04 17:03 Robert F. Garry open

circumstantial and speculation is all it seems.
2020-05-04 17:11 Robert F. Garry open

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112090/
2020-05-04 17:13 Robert F. Garry

Drosten sorta comes out and says it too. "The emergence of HCoV-OC43 in humans was proposed to be linked to a host-switching event around the year 1890, a time that coincides with a pandemic of respiratory disease recorded inhumans (Vijgen et al., 2005, 2006)."
2020-05-04 17:13 Robert F. Garry open

OC43 is intersting...

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