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Slack / Private Message Drop, p.9 [SLACK_000223] · slack_pm:msg:00087

Page text: p.9 · original PDF

Date
2020-05-04 16:54
Type
chat message · slack
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry
Topics
Furin cleavage site and molecular features

Recipients on this medium are inferred from channel membership, not per-message addressing.

Yes - but the article also says that OC43 caused the 1898 Russian flu. I thought it was H3N8. Is this true aboutOC43 or don't we know. OC43 has a furin site and O-glycans.

In context

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  1. 2020-05-04 16:20 Kristian G. Andersen open
    From this otherwise excellent overview - wtf?? [shared file(s): Screen Shot 2020-05-04 at 4.19.57 PM.png]
  2. 2020-05-04 16:20 Kristian G. Andersen open
    https://media.nature.com/original/magazine-assets/d41586-020-01315-7/d41586-020-01315-7.pdf
  3. 2020-05-04 16:21 Kristian G. Andersen open
    Do people honestly think magic will save us? Several good quotes by Bob and Andrew though :wink:
  4. 2020-05-04 16:30 Edward C. Holmes open
    I'm 100% certain he said a lot more than that - and was very reasonable - but the journo has just picked specific quotes and chosen the context. That particularly Nature reporter has form and I refuse to talk to him.
  5. 2020-05-04 16:54 Robert F. Garry
    Yes - but the article also says that OC43 caused the 1898 Russian flu. I thought it was H3N8. Is this true aboutOC43 or don't we know. OC43 has a furin site and O-glycans.
  6. 2020-05-04 16:56 Edward C. Holmes open
    There can't be any evidence it is OC43, surely?
  7. 2020-05-04 17:03 Robert F. Garry open
    circumstantial and speculation is all it seems.
  8. 2020-05-04 17:11 Robert F. Garry open
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112090/
  9. 2020-05-04 17:13 Robert F. Garry open
    Drosten sorta comes out and says it too. "The emergence of HCoV-OC43 in humans was proposed to be linked to a host-switching event around the year 1890, a time that coincides with a pandemic of respiratory disease recorded inhumans (Vijgen et al., 2005, 2006)."

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