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Slack / Private Message Drop, p.9 [SLACK_000223] · slack_pm:msg:00088

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There can't be any evidence it is OC43, surely?

In context

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2020-05-04 16:20 Kristian G. Andersen open

https://media.nature.com/original/magazine-assets/d41586-020-01315-7/d41586-020-01315-7.pdf
2020-05-04 16:21 Kristian G. Andersen open

Do people honestly think magic will save us? Several good quotes by Bob and Andrew though :wink:
2020-05-04 16:30 Edward C. Holmes open

I'm 100% certain he said a lot more than that - and was very reasonable - but the journo has just picked specific quotes and chosen the context. That particularly Nature reporter has form and I refuse to talk to him.
2020-05-04 16:54 Robert F. Garry open

Yes - but the article also says that OC43 caused the 1898 Russian flu. I thought it was H3N8. Is this true aboutOC43 or don't we know. OC43 has a furin site and O-glycans.
2020-05-04 16:56 Edward C. Holmes

There can't be any evidence it is OC43, surely?
2020-05-04 17:03 Robert F. Garry open

circumstantial and speculation is all it seems.
2020-05-04 17:11 Robert F. Garry open

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112090/
2020-05-04 17:13 Robert F. Garry open

Drosten sorta comes out and says it too. "The emergence of HCoV-OC43 in humans was proposed to be linked to a host-switching event around the year 1890, a time that coincides with a pandemic of respiratory disease recorded inhumans (Vijgen et al., 2005, 2006)."
2020-05-04 17:13 Robert F. Garry open

OC43 is intersting...