Private channel session 436
68 messages over 2h 28m, 2020-10-01 – 2020-10-01.
A “conversation” here is an activity session — a run of messages with under 60 minutes of silence inside it. The channel had no native conversation boundaries.
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Eddie Holmes is no longer my friend on Twitter :crying_cat_face: - Eddie, I take this as my queue to shut up... :stuck_out_tongue_winking_eye:. In better news - we can only hope... [pun intended] https://www.nytimes.com/live/2020/10/01/us/trump-vs-biden?action=click&module=Top%20Stories&pgtyp e=Homepage#hope-hicks-coronavirus
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Pretty interesting genomic report from New Zealand (confidential for now, I assume) that looks well-reasoned: https://nextstrain.org/community/narratives/ESR-NZ/GenomicsNarrativeSARSCoV2/2020-10-01
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This looks weird: https://osf.io/s4td6/ There was a simultaneous outbreak of the zoonotic Nipah henipavirus in Wuhan - 4 out of 5 patients have the virus in Jinyintan Hospital , along with SARS-Cov2, in their metagenome - which seems to have resolved by itself *AUTHORS* Sandeep Chakraborty
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But yes if not prayers we at least have hope! Either he gets it or a HCQ/Azithromycin overdose.
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Hmmmm that IS weird. Presumably though, if these reads are real surely they must be contamination from other sequencing experiments at WIV.
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E.g., I know people found plenty of evidence of Lassa in GTEx individuals from the Broad... Obviously there was nooutbreak of Lassa in Boston - just the Broad doing its thing.
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Yeah, I'm pretty sure these are contaminants - you can see the reads via the raw SRA: https://trace.ncbi.nlm.nih.gov/Traces/sra/?run=SRR11092059 https://trace.ncbi.nlm.nih.gov/Traces/sra/?run=SRR11092060 https://trace.ncbi.nlm.nih.gov/Traces/sra/?run=SRR11092061 https://trace.ncbi.nlm.nih.gov/Traces/sra/?run=SRR11092062 Many other viruses in there too
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I'm now your friend again @Kristian Andersen...I obviously unfollowed by mistake. :older_man:
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Of course... It's okay Eddie - I want to unfollow myself as well :wink:
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Have a look at this one: https://trace.ncbi.nlm.nih.gov/Traces/sra/?run=SRR11092059&krona=on
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Let's hope that Hope was spreading things around on Trump's chopper.
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LOTS of viruses in there - obviously contaminants. I'm surprised the tinfoil hats haven't picked up on it yet. YET.
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Yeah - reminds me of the rotavirus in the BASV metagenomic data. Not going to stop the Alina' and Yan's of the world from building a mountain, Yeah they picked it up the DRASTIC crowd.
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Yup.
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What other viruses are you seeing in there?
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Lots... If you click on the Krona plot above then "virus" in the bottom right
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Oh, now I see....
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If you limit "Max depth" to 4 then you get a better view
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Most flu + SARS2 - with a bit of Nipah
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... and clearly Nipah work going on at WIV: https://www.researchgate.net/profile/Zhengli_Shi
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Yes, they must have all escaped simultaneously and ended-up in the same patients but no one else. That's the obvious explanation.
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Well, obviously.
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Perhaps another clever distraction like the "made-up" RatG13?
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Did you look in our patient as well? https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA603194
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Just don't tell me there is Nipah v in there.
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I'd be OK with a cricket virus - maybe a nice fish filovirus.
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Ohhh boy...
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Pretty darn certain there as no Nipah in there!
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THERE'S 61% DARK MATTER!!!!!!! [shared file(s): Screen Shot 2020-10-01 at 8.18.04 PM.png]
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Spooky!
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I know. Clearly made up.
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https://trace.ncbi.nlm.nih.gov/Traces/sra/?run=SRR10971381&krona=on
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[nothing to see - so boring :wink: ]
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Oh my - good thing we went to two-factor encryption.
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Which one is that Kristian?
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That's yours
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Thought so. We hid it well.
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Yup
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Did you see before? [shared file(s): WeChat Image_20200103182929.jpg]
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This must be amplicon/enriched sequencing, right? Not metagenomic?
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What's that Eddie?
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No. Shotgun with rRNA depletion.
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That's the original sequencing report from mid-late December where the commercial company first found reads for 'SARS'.
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59 reads and spent everyone into major panic.
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Ah, interesting. And this didn't get to George? I mean - 59 SARS reads is a pretty red flag. Mid December?
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I'll try to get you the exact date. George bloody knew!!!
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Yeah, I have a REALLY hard time seeing how George wouldn't have known (I think it was the interview with Zhang where it was mentioned? And btw - Zhang = Times 100, which is pretty cool!)
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He bloody knew. No doubt. Yes, I was the go-between with TIME and Zhang. I told him not to do it - I thought there might be trouble - but his ego got the better of him.
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Zhang has now been booted out of China CDC and is now full-time in Shanghai. George is absolutely furious with him for stealing his glory. At the end of the day, it's allo about ego.
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The other thing is that sequencing report I sent was from WeChat. This chat was all over social media in China. And yet there is no chat about nothing from WIV.
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Oh, and obviously, our patient was sequenced in Shanghai (and was a fish market worker). So, clearly sequencing contamination at WIV.
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Trump begins quarantine as close aide Hope Hicks tests positive for coronavirus President Trump told Fox News's Sean Hannity during a live interview Thursday night that he and the first lady were tested after they learned about Hicks and were planning to quarantine. Hicks traveled with the president several times this week.
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Trump in quarantine is a pretty big deal - this will be interesting...
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Let's hope he stays there.
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For the next 20 years.
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> Zhang has now been booted out of China CDC and is now full-time in Shanghai. George is absolutely furious with him for stealing his glory. At the end of the day, it's allo about ego. Yeah, I can see that... I didn't think about that with Time 100, but obviously that must have pissed off George like nothing else.
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George wanted to the global hero on COVID. Discovered the virus, Nobel prize etc.
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Didn't quite go according to plan...
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He's been furious with Zhang since we released the sequence.
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In other news, this look good: [shared file(s): 120475767_10218533870683604_3529426926273920355_n.jpg]
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Must be set in New Orleans. Steamy down there.
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I wouldn't be surprised if MJ Edwards is actually a pseudonym for RF Garry...
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Indeed. I can see no reason why RF Garry couldn't have come up with this: [shared file(s): iovzfsw1g4q51.jpg]
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Not sure - Bob would never say "Indeedily"
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I need to get 'Indeedily' into a paper.
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You do that - I'll try to incorporate the rest....
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I wonder what will happen when Alexa starts some alignments?
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https://twitter.com/realDonaldTrump/status/1311892190680014849?s=20