Slack / Private Message Drop — page 528

I think it is probably the first major human adaptation [2021-02-19 14:48:32] [Robert Garry] Remarkable! [2021-02-19 14:50:43] [Robert Garry] I think that all of the natural human-to-animals have been DouG/PhiL, but the fact that a PreDoug virus converted to PhiL in 10/10 monkeys is crazy... [2021-02-19 14:50:45] [Kristian Andersen] [thread - ID: 2021-02-19 14:50:45] So why're we talking about "Doug took over the world"? I'd be _much_ more inclined to think Phil did and brought his friend Doug with him [2021-02-19 14:56:13] [Robert Garry] Just an impression but many [not all] of the places the nonPhiL viruses are lingering seem to be relatively low incidence countries. [2021-02-19 15:11:02] [Robert Garry] RaTG13 and SC1 have the proline at that site. [2021-02-19 15:12:41] [Kristian Andersen] Proves it came from the lab. [2021-02-19 15:19:16] [Robert Garry] Don't tell Yuri, Alina or Billy the one-eyed dead monkey. [2021-02-20 00:18:13] [Andrew Rambaut] [thread - ID: 2021-02-19 14:50:45] @Kristian Andersen Yes - that is the hypothesis that the people with the monkeys are talking about. [2021-02-20 07:11:40] [Andrew Rambaut] Interesting though is A.23.1 with Doug's neighbour Qeith. It has NSP12 Y346H - related? [2021-02-20 07:12:18] [Andrew Rambaut] (also 681R of course) [2021-02-20 07:14:59] [Andrew Rambaut] Full complement is: Spike: F157L, V367F, Q613H, P681R, R102I N: Q39R, S202N NS8: L84S, E92K NSP4: T495I NSP6: L98F, M183I, M86I