Slack / Private Message Drop — page 346

[Kristian Andersen] @Robert Garry - not sure if there were changes in the passaged viruses - something to ask Mark when he's back (1/4 - same for the rest of the lab). [2020-12-28 17:28:59] [Eddie Holmes] [thread - ID: 2020-12-28 14:44:55] @Eddie Holmes And here's a simplot. There's clearly a region from ~8-18 Kb where it is about as close to SARS-CoV-2 as RaTG13... [shared file(s): SimPlot.bmp] [2020-12-28 17:35:03] [Kristian Andersen] [thread - ID: 2020-12-28 14:44:55] @Eddie Holmes Interesting stuff going on in ORF1 too [2020-12-28 17:35:20] [Eddie Holmes] [thread - ID: 2020-12-28 14:44:55] @Eddie Holmes Indeed. [2020-12-28 17:36:09] [Kristian Andersen] [thread - ID: 2020-12-28 14:44:55] @Eddie Holmes I hate coronaviruses - so many trees across different parts of the genome - clearly they're just shuffling shit around like they were bacteria. Pretty concerning. [2020-12-28 17:47:21] [Eddie Holmes] [thread - ID: 2020-12-28 14:44:55] @Eddie Holmes Yes, and trying to work out the exact history of recombination events is bloody difficult. [2020-12-28 20:26:02] [Robert Garry] [thread - ID: 2020-12-28 14:44:55] @Eddie Holmes Super interesting. Yeah 8-18K - Both similar to SC2, so PH and RatG13 must be very similar to each other in this region. Stick another nail in the coffin containing that rotting corpse alleging that RaTG13 is a made-up virus. [2020-12-29 07:09:27] [Kristian Andersen] Frankie Bollocks is going all epi on the new variant with some great basic insights. https://twitter.com/ballouxfrancois/status/1343846180116193280?s=21 [2020-12-29 07:11:43] [Andrew Rambaut] Along with: https://twitter.com/BallouxFrancois/status/1343878143925493766?s=20 [2020-12-29 07:12:00] [Andrew Rambaut] "Low powered test fails to discover something once again, shock" [2020-12-29 07:17:37] [Kristian Andersen]