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Slack / Private Message Drop, p.1100 [SLACK_001314] · slack_pm:msg:11467

Date: 2022-03-25 16:57
Type: chat message · slack
mentioned: Kristian G. Andersen
recipient: Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker: Robert F. Garry

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Also as @Kristian Andersen noted something up with the glycosylation sites. BA.2 loses its first N-linked site (whichis unlike any other variant of concern AFAIK), but interestingly to me BA.2 picks up a predicted O-linked glycan at349 that is also present in the BANAL viruses.

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2022-03-25 16:54 Robert F. Garry open

https://virological.org/t/spike-protein-mutations-in-novel-sars-cov-2-variants-of-concern-commonly-occur-in-or-near-indels/605 I'm wondering if we shouldn't update the INDEL virological post with BA.1 and BA.2. The association ofthe Omicron mutations in BA.1 and BA.2 with indels is *even more pronounced*. Started to draft an alignment, but this should also included Alpha, Beta and Gamma. [shared file(s): image.png]
2022-03-25 16:57 Robert F. Garry

Also as @Kristian Andersen noted something up with the glycosylation sites. BA.2 loses its first N-linked site (whichis unlike any other variant of concern AFAIK), but interestingly to me BA.2 picks up a predicted O-linked glycan at349 that is also present in the BANAL viruses.

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