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Slack / Private Message Drop, p.820 · slack_pm:msg:08556

Page text: p.820 · original PDF

Date
2021-05-16 06:55 (hour precision)
Type
chat message · slack
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry
Topics
Biosafety and biosecurityCongressional oversightGain-of-function research

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https:/Awww.nationalreview.com/news/biosafety-expert-explains-why-faucis-nih-gain-of-function-testimony-was-dem onstrably-false/

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https:/Awww.nationalreview.com/news/biosafety-expert-explains-why-faucis-nih-gain-of-function-testimony-was-dem onstrably-false/ needs context speaker_own asserts

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  1. 2021-05-16 06:55 Robert F. Garry open
    https//www.ncbi.nim.nih.gov/pmc/articles/PMC5309958/ This little paper from @Eddie Holmes and references therein is highly relevant to the hku-1 analogy, which is spot-on.
  2. 2021-05-16 06:55 Robert F. Garry open
    OC43 is relevant- worth remembering that NL63 and HKU-1 were discovered after SC1 and as a result of virus hunting driven by SC1. https://www.ncbi.nim.nih.gov/pmc/articles/PMC3194943/ "Before the SARS epidemic in 2003, there were only 19 known coronaviruses, including 2 human, 13 mammalian, and 4 avian coronaviruses. After the SARS epidemic, more than 20 additional novel coronaviruses have been described with complete genome sequences (9, 24-26, 31, 42, 45, 50, 53, 54, 57). These include 3 human coronaviruses, 15 mammalian coronaviruses, and 4 avian coronaviruses. For human coronaviruses, human coronavirus NL63 (HCoV-NL63) (an alphacoronavirus) and human coronavirus HKU1 (HCoV-HKU1) (a betacoronavirus) have been discovered in addition to the two previously known human coronaviruses, human coronavirus 229E (HCoV-229E) (an alphacoronavirus) and human coronavirus OC43 (HCoV-OC43) (a betacoronavirus), as well as SARS-CoV (a betacoronavirus) (9, 45, 53, 56)"
  3. 2021-05-16 06:55 Robert F. Garry open
    https://pubmed.ncbi.nlm.nih.gov/29551 135/" *HCoV-OC43 is thought to have emerged from ancestors in domestic animals such as cattle or swine.* The bovine coronavirus has been suggested to be a possible ancestor, from whichHCoV-OC43 may have emerged in the context of a *pandemic recorded historically at the end of the 19th century*. New data suggest that HCoV-229E may actually be transferred from dromedary camels similar to Middle East respiratory syndrome (MERS) coronavirus. This scenario provides important ecological parallels to the presentprepandemic pattern of host associations of the MERS coronavirus."
  4. 2021-05-16 06:55 Robert F. Garry open
    https://www.ncbi.nim.nih.gov/pmc/articles/PMC7232417/ may not be best ref but MERS-CoV - outbreaks have been linked to camel slaughterhouses
  5. 2021-05-16 06:55 Robert F. Garry
    https:/Awww.nationalreview.com/news/biosafety-expert-explains-why-faucis-nih-gain-of-function-testimony-was-dem onstrably-false/
  6. 2021-05-16 06:55 Robert F. Garry open
    eDim says Fauci is a liar. You decide which one is lying about the GoF regs.
  7. 2021-05-16 06:55 Andrew Rambaut open
    'Biosafety Expert' :joy:

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