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Slack / Private Message Drop, p.609 [SLACK_000823] · slack_pm:msg:06372

Page text: p.609 · original PDF

Date
2021-03-20 09:40
Type
chat message · slack
recipient
Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker
Kristian G. Andersen

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The 2-3% serological studies were specifically for SARS-like CoVs, with good baselines - so they might well be accurate. But yeah, getting a positive hit on a CoV serological assay - without controlling very closely for background- you can get anything, anywhere.

In context

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  1. 2021-03-20 09:35 Kristian G. Andersen open
    ... in Africa :wink:. That 2-3% number actually has pretty good baselines
  2. 2021-03-20 09:36 Kristian G. Andersen open
    Baseline sampled in e.g., Wuhan - of all places.
  3. 2021-03-20 09:36 Andrew Rambaut open
    OK - baseline cross-reactivity with some sort of CoV
  4. 2021-03-20 09:36 Andrew Rambaut open
    See waste-water in Europe in 2019
  5. 2021-03-20 09:40 Kristian G. Andersen
    The 2-3% serological studies were specifically for SARS-like CoVs, with good baselines - so they might well be accurate. But yeah, getting a positive hit on a CoV serological assay - without controlling very closely for background- you can get anything, anywhere.
  6. 2021-03-20 09:42 Kristian G. Andersen open
    Andrew - since you have a keen eye. Do you know which 'mystery' sequences and viruses Jesse is talking about? I'm quite confused. I think maybe he means these? https://twitter.com/K_G_Andersen/status/1373310963680571397?s=20 Clearly they must be fragments they have managed to successfully sequence, as they mention in the Nature addendum - so absolutely no mystery. Am I missing something?
  7. 2021-03-20 09:43 Andrew Rambaut open
    I was assuming it was those. Some RdRp PCR products I assume
  8. 2021-03-20 09:44 Robert F. Garry open
    Good to be discussing these points ahead of a likely burst of reporting with the relaese of the WHO report! I already have several reporters promising to call.
  9. 2021-03-20 09:45 Kristian G. Andersen open
    ... and then this slide showing that they have managed to get some spike sequences too? Clearly very distant. [shared file(s): EvVevMrXcAA_GmP.jpeg]

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