A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
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I think a scenario of a yearly vaccination with constant updating [stabilized spike of course] is the most likely outcome - and yes it's not the flu so there will a a death toll, so not pretty. Monoclonals (in combo) - again being updated could blunt this. ASnd, some hope for a small molecule drug. Universal CoV vaccine - not so hopeful.
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@Kristian Andersen Yeah - these are not all likely hypotheses I just want to get everything on table.
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Yup, I agree on all of that - with annual updates and us constantly chasing after the virus (which will become easier over time), we'll be fine. My concern is that most people seem to hope for this scenario on "autopilot". Basically, wehave our current vaccines, we'll get them, and it'll be a smooth cruise going forward. I'm not so sure.
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I think I will lay some stuff out there in the B117 paper (which we need to get out quickly because Tulio is being annoying). But then I think a nice piece in Science or Nature to bring it all together?
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2021-02-20 10:29
Andrew Rambaut
Basically - a "what the fuck just happened" piece?
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I think bringing it all together would be really important and helpful to a lot of people - so I'm a yes on that plan.
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Basically fleshing out a little more _many_ of the points already made in this thread. Maybe we can deploy some AIto scan through our text and write the paper for us...
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Is that what you refer to your grad students as?
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"Eddie Holmes", actually - but close.