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Slack / Private Message Drop, p.441 [SLACK_000655] · slack_pm:msg:04563

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Just going through my emails for the GIPA crap. Some are poignant. [shared file(s): Screen Shot 2021-01-24 at 9.27.27 am.png]

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2021-01-23 13:20 Edward C. Holmes open

@Robert Garry The sequence of the Cambodian bat virus is now on GISAID. Not sure if you have it. Also, do you/we plan to write-up these Virological posts into a paper? Things are moving quickly though.
2021-01-23 13:39 Andrew Rambaut open

More seriously - what would be the optimal FCS?
2021-01-23 13:41 Andrew Rambaut open

And of course optimal cleavage may not have peak fitness benefit to the virus - you can presumably cleave too well and alter some other trade off in the dynamics.
2021-01-23 14:28 Andrew Rambaut open

Genomes - England per day. Red = B.1.1.7, Blue = B.1.177, Grey = the rest [shared file(s): image.png]
2021-01-23 14:36 Edward C. Holmes

Just going through my emails for the GIPA crap. Some are poignant. [shared file(s): Screen Shot 2021-01-24 at 9.27.27 am.png]
2021-01-23 14:37 Edward C. Holmes open

Note the date
2021-01-23 14:40 Andrew Rambaut open

Will these be made public?
2021-01-23 14:46 Edward C. Holmes open

No plans to. They don't directly relate to the paper.
2021-01-23 14:51 Robert F. Garry open

@Andrew Rambaut Agree with this - optimal cleavage might vary depending on multiple factors - cleave in the wrong tissue or wrong time not good. - An optimal cleavage site is RRXRR. Not all X's equal so RRRRR among the best.