Chat message

Slack / Private Message Drop, p.430 [SLACK_000644] · slack_pm:msg:04439

Date: 2021-01-20 08:25
Type: chat message · slack
recipient: Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker: Robert F. Garry

Recipients on this medium are inferred from channel membership, not per-message addressing.

Anyway I'm pretty much done with the revised text . Everyone under water of course and SUPER busy, but when I get the thumbs up from the channel I'll go ahead and post... Check the last p[aragraph of the discussion for the major change and incorporation of the Tommy data.

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2021-01-20 08:02 Robert F. Garry open

There is a ton of mischief changing L452R could do. Likely a neutralizing epitope of course. The positive charge onR likely changes the interactions with several other chains. This could improve the interaction between Y453 andH34 on ACE2.
2021-01-20 08:14 Robert F. Garry open

shared file(s): image.png
2021-01-20 08:17 Robert F. Garry open

Blue: L452R, Black Y453, Orange H34 ACE2
2021-01-20 08:23 Robert F. Garry open

@Eddie Holmes not sure if Tommy got the link. Not sure (tech?) but I think anyone with this link can log on. https://docs.google.com/document/d/1UMQokOz_gDqE0s9keyI7ES8bC7-55EOFuA4UiznEP08/edit
2021-01-20 08:25 Robert F. Garry

Anyway I'm pretty much done with the revised text . Everyone under water of course and SUPER busy, but when I get the thumbs up from the channel I'll go ahead and post... Check the last p[aragraph of the discussion for the major change and incorporation of the Tommy data.

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