Chat message

Slack / Private Message Drop, p.404 [SLACK_000618] · slack_pm:msg:04167

Date: 2021-01-15 12:44
Type: chat message · slack
recipient: Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker: Kristian G. Andersen

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@Kristian Andersen Yeah, that'll be important to have, however, I'd love to have a way to "look up" particular mutations - e.g., E484K telling me it increases affinity and is involved in immune escape - so more on the functional side to make sense of the phylogenetic data. Would be similar to Jesse's 'maps', but with much more information. Not an easy task at all though...

In context

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2021-01-15 11:50 Kristian G. Andersen open

Yeah, please keep that confidential for now - the zoo is freaking out... That genome is identical to a zookeeper, sono change of the virus going to the gorilla. We're getting additional samples.
2021-01-15 12:23 Robert F. Garry open

Will do - test some monkeys too. Maybe the tamarins. They are my favorites.
2021-01-15 12:33 Kristian G. Andersen open

It'll be interesting to see if the whole zoo goes down with covid....
2021-01-15 12:41 Andrew Rambaut open

@Kristian Andersen We are building a website that will track 'constellations' rather than variants. Combinations ofmutations of known or predicted importance. Were you can cross cut the data to see where those combinations have arisen and in what contexts (independent of the phylogenetic history).
2021-01-15 12:44 Kristian G. Andersen

@Kristian Andersen Yeah, that'll be important to have, however, I'd love to have a way to "look up" particular mutations - e.g., E484K telling me it increases affinity and is involved in immune escape - so more on the functional side to make sense of the phylogenetic data. Would be similar to Jesse's 'maps', but with much more information. Not an easy task at all though...
2021-01-15 12:48 Robert F. Garry open

Would be sad - my three favorite zoos happen to be in NOLa, San Diego and Sydney.
2021-01-15 12:49 Kristian G. Andersen open

Separately - can I just point out that it's 85 degrees in San Diego today. I thought it was winter..?! :beach_with_umbrella:
2021-01-15 13:37 Edward C. Holmes open

I'm particularly partial to gibbons.
2021-01-15 13:51 Kristian G. Andersen open

Possibly the second best thing on Twitter today (after Andrew's Variant Rant) https://twitter.com/mbeisen/status/1350181257313882112?s=20

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