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1. 2021-01-14 13:11 Andrew Rambaut open
   Jeez: ```We report the presence of a viral isolate from late December 2020 in Columbus Ohio that has acquired the S N501Y variant. This amino acid change was first described in a clinical sample in the United Kingdom in association with other novel S variants and a clade 20B backbone (ECDC, 2020; Davies et al, 2020), with the combination named as the B.1.1.7 strain and a Next Strain designation as 20I/501Y.V1 (Bedford et al, 2021). The same N501Ymutation was subsequently found in a clade 20C strain in South Africa, where it was associated with a different setof additional S variants (Tegally et al, 2020), with Next Strain designation as 20H/501Y.V3. ```What a fucking mess Trevor has created. "It has acquired the N501Y variant".
2. 2021-01-14 13:19 Andrew Rambaut
   On that note, I am sure I read this hypothesis somewhere before: https://twitter.com/trvrb/status/1349774308202094594
3. 2021-01-14 13:23 Edward C. Holmes open
   Aye on both counts. Fucking Trevor!
4. 2021-01-14 13:25 Andrew Rambaut open
   That Ohio paper is well out of order. They say - UKnB.1.1.7 (clade 20I/501Y.V1) strain. This is not on - you can'tlabel stuff geographically.
5. 2021-01-14 13:26 Andrew Rambaut open
   `containing several likely pathogenic but distinct mutations in the Spike (S) gene, particularly N501Y.` - what? 'likelypathogenic'? Garbage
6. 2021-01-14 13:30 Edward C. Holmes open
   I think you can give this one a kicking on Twitter. Unfortunately, given the discussion about it yesterday I think I hadto post it. The reviewers can resolve all that stuff.

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