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Slack / Private Message Drop, pp.380-381 [SLACK_000594] · slack_pm:msg:03960

Page text: p.380, p.381 · original PDF

Date
2021-01-11 15:06
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker
Andrew Rambaut

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```ORF1ab synT733C F681L I760T synC2749T S1188L K1795Q del11288-11296 (3675-3677 SGF) synC12778T synC13860T E5662D spike L18F T20N P26S D138Y R190S K417T E484K N501Y H655Y T1027I ORF3a: C174G ORF8: E92K N: P80R synA28881T synG28882C```

In context

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  1. 2021-01-11 14:43 Edward C. Holmes open
    Wowser. That's not chance.
  2. 2021-01-11 14:51 Robert F. Garry open
    Places where the polymerase has tendency to slip and skip?
  3. 2021-01-11 15:05 Andrew Rambaut open
    The Manaus/Japanese cluster has a very long branch (too long) - possibly another 'chronic infection' event?
  4. 2021-01-11 15:06 Kristian G. Andersen open
    What does nsp6 do again? Is it possible it's directly interacting with the spike protein to determine e.g., binding?
  5. 2021-01-11 15:06 Andrew Rambaut
    ```ORF1ab synT733C F681L I760T synC2749T S1188L K1795Q del11288-11296 (3675-3677 SGF) synC12778T synC13860T E5662D spike L18F T20N P26S D138Y R190S K417T E484K N501Y H655Y T1027I ORF3a: C174G ORF8: E92K N: P80R synA28881T synG28882C```
  6. 2021-01-11 15:06 Kristian G. Andersen open
    Bloody hell
  7. 2021-01-11 15:07 Edward C. Holmes open
    WTF.
  8. 2021-01-11 15:08 Andrew Rambaut open
    Just bonkers
  9. 2021-01-11 15:08 Kristian G. Andersen open
    Where did they do the AZN trials again?

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