A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
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Lot of immunosuppressed Africans, HIV and other causes, as well. So having the P681 changes may fit that meme.
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This is the new USA cluster with Eeek and Pooh: [shared file(s): image.png]
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All in Maryland? Worth keeping an eye on it for sure...
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This one only has 484K but spans 4 months and 4 states: [shared file(s): image.png]
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2021-01-09 08:14
Andrew Rambaut
@Robert Garry Perhaps it was around the Capitol on Tuesday
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@Robert Garry That would be ironic if that likely super-spreader event spreads a new "super" variant.
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Eaak and Pooh are the ones that worry me the most. I think we're in for a wild ride
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I am trying to decide if this is a 'phase-change' in the evolution of the virus (i.e., driven by standing immunity) or is itjust that now there are simple enough cases that these combinations (of previously individual mutations) are startingto appear together and so the synergies are apparent.
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I would not rule out that some of the Pooh-related mutations are immune driven as well - some of the christmas card mutations near the FCS could well be epitopes.https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0238089