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Slack / Private Message Drop, p.302 [SLACK_000516] · slack_pm:msg:03153

Date: 2020-12-06 12:33
Type: chat message · slack
recipient: Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker: Andrew Rambaut

Recipients on this medium are inferred from channel membership, not per-message addressing.

Curious though that the Malaysian one is one SNP closer to RmYN02 than all the others. So possibly that one (but the January cases in Malaysia were Chinese nationals visiting)

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2020-12-06 12:08 Edward C. Holmes open

Total sense and I fully agree. I suspect the emergence event took place elsewhere and was imported into Wuhan.
2020-12-06 12:09 Edward C. Holmes open

Can you just summarise where the root should fall? I didn't follow all that chain.
2020-12-06 12:11 Kristian G. Andersen open

WA1
2020-12-06 12:27 Andrew Rambaut open

And by WA1 we mean a haplotype identical to WA1 that was in Wuhan before the 15th January
2020-12-06 12:33 Andrew Rambaut

Curious though that the Malaysian one is one SNP closer to RmYN02 than all the others. So possibly that one (but the January cases in Malaysia were Chinese nationals visiting)
2020-12-06 12:35 Andrew Rambaut open

So I think most parsimonious would be `Malaysia/MKAK-CL-2020-6430|EPI_ISL_416886|2020-02-04` -> `WA1` -> `WH04` -> `Wuhan-Hu-1`
2020-12-06 12:35 Andrew Rambaut open

(but all in Wuhan)
2020-12-06 12:36 Kristian G. Andersen open

Would it be worth trying to simulate a WA1 with a date in the beginning of December and run beast?
2020-12-06 12:38 Andrew Rambaut open

shared file(s): image.png

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