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Slack / Private Message Drop, p.301 [SLACK_000515] · slack_pm:msg:03141

Page text: p.301 · original PDF

Date
2020-12-06 11:18
Type
chat message · slack
recipient
Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker
Kristian G. Andersen

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I'm heading out for an hour, but once I'm back lemme just clean up these alignments a little and share - just so wehave them archived here. :beer:

In context

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  1. 2020-12-06 11:15 Kristian G. Andersen open
    I think it's safe to say that we're definitely missing some early emergence stuff here
  2. 2020-12-06 11:16 Kristian G. Andersen open
    ... which is very interesting and worth a closer look. Would explain why we can't really root properly as well (Ihaven't checked recently, but back in the spring, BEAST insisted on a midpoint root when you took away the dates).
  3. 2020-12-06 11:16 Andrew Rambaut open
    Will do some experiments on BEAST dating with enforced WA1 outgrouping
  4. 2020-12-06 11:17 Kristian G. Andersen open
    Okay, cool - I'll have a chat with Karthik too - we haven't been able to get good estimates of the root TMRCA recently, but that may very well be on us.
  5. 2020-12-06 11:18 Kristian G. Andersen
    I'm heading out for an hour, but once I'm back lemme just clean up these alignments a little and share - just so wehave them archived here. :beer:
  6. 2020-12-06 11:38 Andrew Rambaut open
    > On January 21, the Centers for Disease Control and Prevention (CDC) confirmed the first U.S. case in a 35-year-old man living in Snohomish County. He had returned from Wuhan, China after visiting his family there, tothe U.S., landing at Seattle-Tacoma International Airport on January 15, without any symptoms.
  7. 2020-12-06 11:41 Andrew Rambaut open
    And of course at that time Imperial College estimated Wuhan had 190-4000 cases by 12th Jan based on 3 exported cases.
  8. 2020-12-06 12:00 Edward C. Holmes open
    @Kristian Andersen They also used my quote out of context...I was just referring to some of those shonky studies, particularly the Indian-origin one.
  9. 2020-12-06 12:02 Kristian G. Andersen open
    Yeah, clearly a lot more cases going around at that time than was appreciated - and obviously not (directly) linked tothe seafood market. We don't really see any evidence of other "WA1" lineages in Wuhan, do we? All those early ones were "Hu-1"?

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