Chat message

Slack / Private Message Drop, p.190 [SLACK_000404] · slack_pm:msg:01963

Date: 2020-09-25 12:30
Type: chat message · slack
recipient: Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker: Robert F. Garry

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I am not a big fan of the way the RCTs are being managed - not one bit. 30-60,000 people being told to go out and get themselves infected is less ethical than the controlled human challenges - just my opinion.

In context

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2020-09-25 12:16 Robert F. Garry open

https://www.ft.com/content/b782f666-6847-4487-986c-56d3f5e46c0b
2020-09-25 12:18 Robert F. Garry open

Interesting article NIH awarded a contract to CSU to grow it's own challenge strain.
2020-09-25 12:18 Kristian G. Andersen open

Yup, saw that yesterday - still not sure what I feel about it :wink:
2020-09-25 12:27 Robert F. Garry open

Angie_Rasmussen others still not a fan of it. Your way - small 30 people no placebo trials would be a good screen IMO. High Risk - High Reward US still losing ~1000 per day.
2020-09-25 12:30 Robert F. Garry

I am not a big fan of the way the RCTs are being managed - not one bit. 30-60,000 people being told to go out and get themselves infected is less ethical than the controlled human challenges - just my opinion.
2020-09-25 12:51 Kristian G. Andersen open

Yeah, I'm not a fan of the RCTs either - I don't think they'll tell us what we need to know robustly and quickly enough. I kinda liked the German experiment where they set up relatively high-risk settings (during a concert) tobetter understand how transmission works. So a strategy that I kinda like here would be akin to a "COVID Party" strictly with people that are vaccinated - no control group. No need to figure out dosing, isolates, etc., which is far from trivial.
2020-09-25 13:06 Robert F. Garry open

:beer::beer::beer::beer::beer: would probably make the experiment work better.
2020-09-25 13:07 Robert F. Garry open

But I really like the idea.
2020-09-25 13:08 Kristian G. Andersen open

I think *any* party in the UK involves copious amounts of exactly that, so that goes without saying... :stuck_out_tongue_winking_eye:

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