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Slack / Private Message Drop, p.167 [SLACK_000381] · slack_pm:msg:01719

Page text: p.167 · original PDF

Date
2020-09-14 23:41
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker
Edward C. Holmes

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Fuck, that's cunning.

In context

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  1. 2020-09-14 23:40 Edward C. Holmes open
    I'm all for it then.
  2. 2020-09-14 23:41 Andrew Rambaut open
    Ooh. Just saw this bit: ```Since many phylogenetic analyses categorize coronaviruses based on the sequence similarity of the RdRp gene only SARS-CoV-2 and ZC45/ZXC21 are separated into different groups/sub-lineages in phylogenetic studies.``` So they are saying 'they' used RdRp from a different virus to confuse phylogenetics!
  3. 2020-09-14 23:41 Kristian G. Andersen open
    shared file(s): Screen Shot 2020-09-14 at 11.40.57 PM.png
  4. 2020-09-14 23:41 Andrew Rambaut open
    Then they constructed RaTG13 with that RdRp as well to act as a decoy.
  5. 2020-09-14 23:41 Edward C. Holmes
    Fuck, that's cunning.
  6. 2020-09-14 23:41 Andrew Rambaut open
    But forgot to put the RBD or furin site in.
  7. 2020-09-14 23:42 Edward C. Holmes open
    It was a busy day - they had the lab to bleach.
  8. 2020-09-14 23:42 Kristian G. Andersen open
    They put a restriction site INSIDE the furin site so they can follow the viruses over time - it's all very clever.
  9. 2020-09-14 23:43 Andrew Rambaut open
    I wonder if they encoded any secret messages in the synonymous codon usage?

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