A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
-
So interesting: https://virological.org/t/two-ebola-virus-variants-circulating-during-the-2020-equateur-province-outbreak/538 Man, Ebola evolution has gotten so weird since 2014. It used to be such a well-behaved virus with a logical clock, but that's certainly changed. How interesting.
-
Yeah. The MBK67 has areas of low coverage suggesting a difficult sample. But it has to be survivor relapse/latentinfection, surely?
-
Perhaps which ever bat colony produced the 2018 outbreak had some latently infected bats but seems less likely.
-
2020-08-15 16:01
Andrew Rambaut
Probability of it happening in the middle of another outbreak in the same region? Weird
-
Yeah, MBK67 is super weird, but I talked to Mike earlier in the week and it sounds like it's basal on the clade - I can't quite suss it out from the tree as it's displayed. If that is the case, then it might not actually be a survivor relapse, but rather a new spill-over from the very same reservoir. Very interesting indeed - let's touch base on it with Mike next week too.
-
And yes, from a probability standpoint - two separate outbreaks starting essentially at the same time? Clearly not impossible, but definitely seems risk overall is just up for Ebola - people encroaching on animal habitat I guess.
-
I wouldn't trust the basal thing - it has lots of low coverage areas including over quite a few SNPS internal to the outbreak.
-
Strong ascertainment bias - EVD will be noticed in that area.