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Slack / Private Message Drop, p.123 [SLACK_000337] · slack_pm:msg:01250

Page text: p.123 · original PDF

Date
2020-07-30 14:54
Type
chat message · slack
mentioned
Edward C. Holmes
recipient
Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker
Kristian G. Andersen

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@Eddie Holmes Yeah, Richard and I brought it up at the conference today, but I'm not quite sure they fully understood what the problem was... I kept saying "your analysis assumes growth from one introduction within the country only - the issue is that you have multiple introductions and you have many more G coming in later"... This can only be done on a tree - there's just no way around it.

In context

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  1. 2020-07-30 14:31 Edward C. Holmes open
    You can't do those plots independently for each country. The increase of G in Australia simply relfects the increasing number of imports with this mutation.
  2. 2020-07-30 14:33 Edward C. Holmes open
    Nothing from Jeremy. I therefore suspect he won't email anyone.
  3. 2020-07-30 14:37 Andrew Rambaut open
    @Eddie Holmes Exactly - that is the whole problem with using counts of genomes. We have estimated the growth rate for 50-odd independent introductions into the UK. But it isn't a clean result.
  4. 2020-07-30 14:38 Edward C. Holmes open
    @Eddie Holmes I keep telling people this. Drives me crazy.
  5. 2020-07-30 14:54 Kristian G. Andersen
    @Eddie Holmes Yeah, Richard and I brought it up at the conference today, but I'm not quite sure they fully understood what the problem was... I kept saying "your analysis assumes growth from one introduction within the country only - the issue is that you have multiple introductions and you have many more G coming in later"... This can only be done on a tree - there's just no way around it.
  6. 2020-07-30 14:54 Kristian G. Andersen open
    Hmmm, okay. Should I email Clare?
  7. 2020-07-30 14:56 Edward C. Holmes open
    I'm happy for you to email her.
  8. 2020-07-30 14:57 Kristian G. Andersen open
    Alright - I think we should too, so let me email her now.
  9. 2020-07-30 14:57 Edward C. Holmes open
    With me cc'd.

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