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Slack / Private Message Drop, pp.122-123 [SLACK_000336] · slack_pm:msg:01249

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@Eddie Holmes I keep telling people this. Drives me crazy.

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A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2020-07-30 14:31 Edward C. Holmes open

You can't do those plots independently for each country. The increase of G in Australia simply relfects the increasing number of imports with this mutation.
2020-07-30 14:33 Edward C. Holmes open

Nothing from Jeremy. I therefore suspect he won't email anyone.
2020-07-30 14:37 Andrew Rambaut open

@Eddie Holmes Exactly - that is the whole problem with using counts of genomes. We have estimated the growth rate for 50-odd independent introductions into the UK. But it isn't a clean result.
2020-07-30 14:38 Edward C. Holmes

@Eddie Holmes I keep telling people this. Drives me crazy.
2020-07-30 14:54 Kristian G. Andersen open

@Eddie Holmes Yeah, Richard and I brought it up at the conference today, but I'm not quite sure they fully understood what the problem was... I kept saying "your analysis assumes growth from one introduction within the country only - the issue is that you have multiple introductions and you have many more G coming in later"... This can only be done on a tree - there's just no way around it.
2020-07-30 14:54 Kristian G. Andersen open

Hmmm, okay. Should I email Clare?
2020-07-30 14:56 Edward C. Holmes open

I'm happy for you to email her.
2020-07-30 14:57 Kristian G. Andersen open

Alright - I think we should too, so let me email her now.