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Slack / Private Message Drop, pp.108-109 [SLACK_000322] · slack_pm:msg:01111

Date: 2020-07-27 14:25
Type: chat message · slack
recipient: Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker: Andrew Rambaut

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Yeah. Just some phylogenies, recombination and date estimates of SARS related coronaviruses. Nothing you haven't heard already.

In context

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2020-07-27 13:37 Robert F. Garry open

Nice paper coming Andrew! I hope I did not botch the discussion of the phylogenetic trees, etc. to the reporter toobadly.
2020-07-27 14:05 Andrew Rambaut open

Thanks! More stuff to wind up Ebright and the others.
2020-07-27 14:19 Kristian G. Andersen open

Is this the "Nature Microbiology" paper I have been dodging reporters on today?
2020-07-27 14:25 Andrew Rambaut

Yeah. Just some phylogenies, recombination and date estimates of SARS related coronaviruses. Nothing you haven't heard already.
2020-07-27 14:39 Kristian G. Andersen open

Cool! One interesting thing I got from Trevor though - if he tries to date SARS2 via the related viruses (of which we now have a few), he gets a relatively nice signal for 2014/2015. Doesn't mean anything in isolation, but I still keepcontemplating that 'pre' circulation scenario for emergence. They need to go hunt some more viruses in those Yunnan caves!
2020-07-27 14:40 Andrew Rambaut open

It is meaningless to date SARS2 with related viruses - makes no sense.
2020-07-27 14:41 Kristian G. Andersen open

I thought so too, but honing in on specific parts of the genomes that were homologous it seemed like it could bedone - no idea about the details though.
2020-07-27 14:43 Andrew Rambaut open

It also makes no sense that the SARS2 diversity circulating now was part of the pre-circulating scenario. The Wuhanhaplotype may have been around for a month or two prior to Dec 2019 but not much longer given the transmissibilityof the virus. This virus doesn't lurk unobserved.

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