Chat message

Slack / Private Message Drop, p.104 [SLACK_000318] · slack_pm:msg:01053

Date: 2020-07-23 08:45
Type: chat message · slack
recipient: Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker: Kristian G. Andersen
Topics: Intelligence community assessments

Recipients on this medium are inferred from channel membership, not per-message addressing.

The UK has been playing hard and loose with viruses in the past, so I wouldn't be surprised if we'd see challenge trials from them. IMO, this virus is much too dangerous with too many uncertain long-term effects to deliberately infect people - especially given the HUGE number of cases we have in this country.

Extracted statements

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Statement	Grade	Attribution	Stance
IMO, this virus is much too dangerous with too many uncertain long-term effects to deliberately infect people - especially given the HUGE number of cases we have in this country.	needs context	uncertain explicit hedge	asserts

Statement

Grade

Attribution

Stance

IMO, this virus is much too dangerous with too many uncertain long-term effects to deliberately infect people - especially given the HUGE number of cases we have in this country.

needs context

uncertain explicit hedge

asserts

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2020-07-23 08:14 Andrew Rambaut open

I am talking to Wellcome Vaccines dept tomorrow about challenge trials. They are considering which stocks to manufacture. I am not that sure what to tell them other than a basal D614G.
2020-07-23 08:44 Kristian G. Andersen open

Yeah, NIAID asked us about getting an isolate from a "mild infection"... Well, mild, severe, moderate, chances are they're all the same. I agree on getting something as basal on the tree as possible (that's assuming D614G _does not_ show resistance to neutralization - which is a real concern (e.g., GP A82V in Ebola does that).
2020-07-23 08:45 Andrew Rambaut open

Jeremy's preprint suggests it is sensitive to ABs
2020-07-23 08:45 Andrew Rambaut open

But I guess the point is it is the dominant form and will remain so.
2020-07-23 08:45 Kristian G. Andersen

The UK has been playing hard and loose with viruses in the past, so I wouldn't be surprised if we'd see challenge trials from them. IMO, this virus is much too dangerous with too many uncertain long-term effects to deliberately infect people - especially given the HUGE number of cases we have in this country.
2020-07-23 08:46 Kristian G. Andersen open

Yeah, everything is basically D614G by now, so that's kinda the virus we need to make sure the vaccine works against - but I'm not really concerned there's a difference between Doug and Dougless here.
2020-07-23 08:47 Andrew Rambaut open

I agree that it is probably unnecessary - just try the vaccine.
2020-07-23 08:48 Kristian G. Andersen open

Let's just immunize Florida and see what happens.... :smiling_imp:
2020-07-23 08:51 Robert F. Garry open

I could get begind that

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