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Slack / Private Message Drop — page 68

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We're on the same mailing list Kristian: got that paper as well as the Nature one (which was shite). The Scripps paper looked pretty convincing to me: best evidence I've seen. It was also pretty measured. [2020-06-10 19:09:16] [Kristian Andersen] Yeah, Mike's the boss (he discovered the SARS receptor ACE2, so he knows his shit) [2020-06-10 19:27:31] [Eddie Holmes] Agreed. I was at a meeting with him a few years ago - very, very impressive. [2020-06-10 20:42:25] [Kristian Andersen] I assume this is mostly bullshit - haven't read it yet.. https://www.pnas.org/content/pnas/early/2020/06/09/2008176117.full.pdf [2020-06-10 21:04:04] [Eddie Holmes] Ha! I just downloaded it myself. Conclusions section is interesting....have not read the paper yet. [2020-06-11 04:42:40] [Andrew Rambaut] [thread - ID: 2020-06-10 17:36:17] @Kristian Andersen Jeremy is just about to submit something on this too (he has some cryo-EM stuff too). Perhaps you could mention this to him? Maybe they can coordinate. [2020-06-11 04:44:38] [Andrew Rambaut] So find the closest sequence then. [2020-06-11 06:48:14] [Kristian Andersen] "Machine learning" you know. Fancy stuff. [2020-06-11 06:49:58] [Andrew Rambaut] @Robert Garry @Kristian Andersen Can you tell me anything about the RmYN02 cleavage site insertion? Is it predicted to be furin? [2020-06-11 06:50:03] [Kristian Andersen] [thread - ID: 2020-06-10 17:36:17] @Kristian Andersen Jeremy Luban? I think Mike's study has already been accepted - I got it from NYT. Any insights from the UK data? Or is that part of the paper too? [2020-06-11 06:51:03] [Kristian Andersen] Nope, not a cleavage site - just an insertion (and you'll see a deletion upstream, so it's more of a shift). [2020-06-11 06:59:38] [Andrew Rambaut] Thanks. [2020-06-11 13:31:12]

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slack_pm:msg:00686 2020-06-10 chat message 67–68
slack_pm:msg:00687 2020-06-10 chat message 68
slack_pm:msg:00688 2020-06-10 chat message 68
slack_pm:msg:00689 2020-06-10 chat message 68
slack_pm:msg:00690 2020-06-10 chat message 68
slack_pm:msg:00691 2020-06-11 chat message 68
slack_pm:msg:00692 2020-06-11 chat message 68
slack_pm:msg:00693 2020-06-11 chat message 68
slack_pm:msg:00694 2020-06-11 chat message 68
slack_pm:msg:00695 2020-06-11 chat message 68
slack_pm:msg:00696 2020-06-11 chat message 68
slack_pm:msg:00697 2020-06-11 chat message 68
slack_pm:msg:00698 2020-06-11 chat message 68–69