Slack / Private Message Drop — page 610

Also this tree, but I suspect that the same I just linked to, and yes, probably RdRp. Same IDs, so clearly the same. And clearly, they don't have the full genomes (because, well, bloody hard to do) [shared file(s): Ew35lxKU8AAbXdw.png] [2021-03-20 09:50:18] [Robert Garry] @Andrew Rambaut points well taken re cross-reactivity - even the best seroassays are not 100% - the paper we referenced in PO1 and the one Daszak is talking about did look for cross-rxty with other covs. https://link.springer.com/article/10.1007/s12250-018-0012-7 cloned most of the known human covs and tested those as well as follow-up western blotting. my take is at least some sarbecovirus reactivity possible. [2021-03-20 10:01:27] [Robert Garry] ...and the cdc paper - which i cant find now - showing seroreactivty to SC2 pre-pandemic was crap. [2021-03-20 10:07:25] [Robert Garry] More crap: https://undark.org/2021/03/18/utterly-plausible-lab-leak-hypothesis/ [2021-03-20 10:14:43] [Robert Garry] Reality: Every one of the zoo's panthers are equipped with chips. The instant the animal left it's perimeter, alerts were sounded and a team was sent to capture it before it escaped the zoo, The zoo has large fence around its perimeter as well. [2021-03-20 10:29:40] [Robert Garry] https://www.sciencemag.org/news/2021/03/major-coronavirus-variant-found-pets-first-time:black_cat::cat2::dog2: oh my. [2021-03-20 10:31:31] [Robert Garry] So --- if it's true that SC2 a "generalist" virus, is it rapidly now becoming more of a generalist virus??? [2021-03-20 10:49:24] [Robert Garry] AS for the panthers there have been 125 panther attacks in the US in the past 100 years - 27 fatalities. All of the attacks were wild panthers - none had escaped from a zoo. [2021-03-20 11:06:23] [Robert Garry] But there is a hypothetical chance that pathers could escape from a zoo, so best- i guess it will be argued - just to shut down all the zoos. [2021-03-20 13:02:35] [Kristian Andersen] Andrew, I hope you at least gave him a breathing tube or cut a hole before you slammed that coffin shut. :coffin::hammer: https://twitter.com/arambaut/status/1373318276848234499?s=20 [2021-03-20 13:58:58] [Robert Garry] WoW- that's fantastic! Way to go Andrew! [2021-03-21 06:32:38]