Slack / Private Message Drop — page 282

[thread - ID: 2020-11-27 10:35:57] Pretty much sure the MRCA of all circulating viruses we have sample so far was one or other of the two original haplotypes. But seems likely to me that it came in to wuhan from somewhere else in China. [2020-11-27 10:36:09] [Andrew Rambaut] shared file(s): Image from iOS.jpg [2020-11-27 10:38:21] [Kristian Andersen] [thread - ID: 2020-11-27 10:35:57] @Andrew Rambaut But that mid-point rooting though..? [2020-11-27 10:41:13] [Kristian Andersen] [desperately trying to find that old Tweet he sent to Oli... I will persevere!] [2020-11-27 10:42:08] [Andrew Rambaut] [thread - ID: 2020-11-27 10:35:57] @Andrew Rambaut Could be something to touch on in the PO2. Some of the RBD mutations we have seen recently (eg mink) are actually reversions to the bat residues. [2020-11-27 10:42:51] [Kristian Andersen] Here it is - it's a true piece of beautiful Twitter history. Nice guy. [shared file(s): 61ED1770-AF57-4BE4-B916-1ED34005C3C6.jpg] [2020-11-27 10:43:27] [Andrew Rambaut] [thread - ID: 2020-11-27 10:35:57] @Andrew Rambaut But of course that is with a non-ACE2 RBD in bats. [2020-11-27 10:44:00] [Kristian Andersen] [thread - ID: 2020-11-27 10:35:57] @Andrew Rambaut Yeah, I definitely think this is something to touch on - I have been intrigued by this question for a long time, but haven't had time to take a closer look (plus, I'm really not the best to look at this question in any case). [2020-11-27 10:44:51] [Kristian Andersen] [thread - ID: 2020-11-27 10:35:57] @Andrew Rambaut Let's maybe wait until we get some more pangos and then look a little closer at the root plus what's going on in mink in terms of reversions? [2020-11-27 12:44:09] [Andrew Rambaut] My whole group follow him for the Twitter pearls. [2020-11-27 13:00:47] [Eddie Holmes] Bob, that arxiv thing was published some months ago in some French journal. Nothing new. The SCMP also contacted me. I've not replied yet but I'm going to tell them to fuck-off as they pulled this through the Freedom of Information act which really pisses me off. Clearly the Italian thing is nutso and if this is pushed the whole WHO thing will loose all credibility as you say, not that it has much any way. I think you can bet good money what when