Slack / Private Message Drop — page 272

[2020-11-21 10:00:15] [Kristian Andersen] Yeah - it seems like a recent mutation in the virus genome might have selected for stupid. [2020-11-21 11:28:49] [Andrew Rambaut] Are there sequences from the beginning and end? Would be interesting to see how many other mutations appear. How many ferrets gets you 1200 mutations? [2020-11-21 12:05:22] [Kristian Andersen] This really is a great tweet... [shared file(s): Screen Shot 2020-11-21 at 12.04.55 PM.png] [2020-11-21 12:46:44] [Robert Garry] Someone should pass that on to Alina, Relman etc.... [2020-11-21 14:37:52] [Eddie Holmes] Yes, great doc Bob. Get it out. Kristian and I have been dealing with some alignment trolls this morning. [2020-11-21 14:38:48] [Andrew Rambaut] Alignment trolls? Who'd have thought we would ever have such things. [2020-11-21 14:40:28] [Eddie Holmes] Yuri Deigin and the powers of BLAST as an alignment tool. I finally blocked him as it was getting so tedious. Proximal Origins 2....I still wonder if we need to wait for more new data? [2020-11-21 14:43:26] [Andrew Rambaut] Quite possibly need more to hang it on. But it might be good to bash out some ideas and see where we are. [2020-11-21 14:45:13] [Eddie Holmes] Don't disagree that with. I would certainly like to take the opportunity to respond to some of the nonsense written about the pangolin viruses. I'll check with Tommy where we are on this. [2020-11-21 14:47:54] [Andrew Rambaut] Also the idea that RaTG13 is a 'progenitor'. [2020-11-21 14:49:49] [Eddie Holmes] Yes! That underpins 99% of the conspiracy stuff. So dumb. And how you end up with a pangolin-like RBD with a RaTG13 as a progenitor? [2020-11-21 14:50:23] [Andrew Rambaut] And when you have RM2 as well [2020-11-21 14:54:06] [Eddie Holmes]