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Slack / Private Message Drop, p.1024 [SLACK_001238] · slack_pm:msg:10701

Page text: p.1024 · original PDF

Date
2021-11-24 07:30
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker
Andrew Rambaut

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Plus 69/70 del and the nsp6 del

In context

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  1. 2021-11-24 07:28 Andrew Rambaut open
    This variant is completely insane - https://github.com/cov-lineages/pango-designation/issues/343
  2. 2021-11-24 07:28 Andrew Rambaut open
    Mutating itself to death, indeed
  3. 2021-11-24 07:29 Andrew Rambaut open
    Check this bit... [shared file(s): image.png]
  4. 2021-11-24 07:30 Andrew Rambaut open
    And a bit of FCS adjacent action... [shared file(s): image.png]
  5. 2021-11-24 07:30 Andrew Rambaut
    Plus 69/70 del and the nsp6 del
  6. 2021-11-24 07:36 Kristian G. Andersen open
    Holy shit - that is quite something. The length of that branch... :scream:. What's the N/S on the branch?
  7. 2021-11-24 07:41 Kristian G. Andersen open
    Just had a look at the list of mutations - so nuts. Getting rid of a lot of serines (although also adding some new ones...) and adding in lysine - the friggin' genome is going to be made out of lysines at some point! Just nuts.
  8. 2021-11-24 08:22 Robert F. Garry open
    Oh boy - it's getting more polybasic - that's not good....
  9. 2021-11-24 08:23 Andrew Rambaut open
    It must surely be from a immunocompromised chronic infection. Possibly a dual infection with recombination and heavy mutation. But the random traveller in HK has me very worried

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