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1. 2021-05-27 19:23 Edward C. Holmes open
   Says the same as our Cell paper re: RaTG13.
2. 2021-05-27 19:35 Robert F. Garry open
   Found this highly interesting: "One possible recent disruption that caused widespread and unusual movements of animals in China and may have increased the permeability of this barrier, was the dramatic shortage of pork products in 2019 attributable to an African swine fever virus (ASFV) outbreak impacting 100s of millions of pigs inChina38. Such a major disruption in the food supply chain will have potentially brought humans into increased contact with Sarbecovirus infected animals as i) exotic meats replaced pork, ii) animals from rural locations were brought to city markets and/or iii) by meat from infected animals being transported in cold chain processes."
3. 2021-05-27 19:37 Kristian G. Andersen open
   I didn't know this bit either: "Still, the fact that viruses in the Yunnan clade (consisting of RmYN02, RpYN06 and PrC31) were sampled from three different Rhinolophus species supports the hypothesis that these viruses readily infect multiple differenthorseshoe bat species with overlapping geographical ranges."Didn't realize they were different species of bats - but, of course, I should, since the naming gives it away.
4. 2021-05-27 19:43 Robert F. Garry open
   Figuring out how the viruses expand their host range even further would be key. Of course, that would require making chimeras which the bloomshitters would frown upon.
5. 2021-05-27 19:45 Kristian G. Andersen
   I found the link to the host range of pangolins quite interesting... https://www.iucnredlist.org/species/12764/168392151
6. 2021-05-27 19:48 Kristian G. Andersen open
   Eddie's point that the nearest virus to SARS-CoV-2 isn't actually one that WIV has also needs repeating! [shared file(s): Recombination tree.png]
7. 2021-05-27 20:27 Edward C. Holmes open
   Not to moan too much, but we said all this in our Cell paper (there's even a whole section on host range mapping).Probably good that it is being said again though.
8. 2021-05-27 20:49 Kristian G. Andersen open
   ... for people like me with a short-term memory, it's good to be reminded again... :wink:
9. 2021-05-27 21:02 Kristian G. Andersen open
   At least that furin cleavage site tweet is coming in handy for the Aussies :scienceparrot: [shared file(s): Screen Shot2021-05-27 at 9.01.45 PM.png]

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