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Slack / Private Message Drop, p.619 [SLACK_000833] · slack_pm:msg:06478

Page text: p.619 · original PDF

Date
2021-03-23 05:47
Type
chat message · slack
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry

Recipients on this medium are inferred from channel membership, not per-message addressing.

Back to the interesting paper - important to keep in mind that enhanced replication in cell culture doesn't necessarilytranslate to enhanced pathogenesis. As Andrew you've noted - it's all about the timing...

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

  1. 2021-03-23 05:19 Andrew Rambaut open
    What do we make of this: https://www.biorxiv.org/content/10.1101/2021.03.22.436468v1.full.pdf
  2. 2021-03-23 05:38 Robert F. Garry open
    Plausible - Indel Region 2 and 3 - very divergent between SC2 and GDpangocov.
  3. 2021-03-23 05:39 Robert F. Garry open
    NTD is the receptor binding domain of many CoVs.
  4. 2021-03-23 05:43 Robert F. Garry open
    Not on this topic but related to "the Plan." Spoke with Betsy McKay again late yesterday- reading between the lines Ibelieve that our friend "Deep Throat" has surfaced again. She was aware of the email exchanges back in January -hinted that they had been shared with her from someone on the calls that thought "we" were a bit overly friendly tothe lab leak.
  5. 2021-03-23 05:47 Robert F. Garry
    Back to the interesting paper - important to keep in mind that enhanced replication in cell culture doesn't necessarilytranslate to enhanced pathogenesis. As Andrew you've noted - it's all about the timing...
  6. 2021-03-23 06:12 Andrew Rambaut open
    Shows how modular the spike is though.
  7. 2021-03-23 06:56 Kristian G. Andersen open
    @Andrew Rambaut Never saw that money from the institution. Bastards.
  8. 2021-03-23 07:00 Kristian G. Andersen open
    I think people are majorly underestimating how flexible and mutational tolerant the spike is.
  9. 2021-03-23 07:37 Robert F. Garry open
    @Andrew Rambaut Rich bastards! :grinning:

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