COVID-19 Records

Chat message

Slack / Private Message Drop, p.575 [SLACK_000789] · slack_pm:msg:06006

Page text: p.575 · original PDF

Date
2021-03-08 13:27
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker
Edward C. Holmes

Recipients on this medium are inferred from channel membership, not per-message addressing.

Such great work from Billy. I'm just surprised he can't get financed.

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

  1. 2021-03-08 13:09 Robert F. Garry open
    "Others argue it is possible there were viruses in the lab, or handled during research, that were not publicly known." This is it in a nutshell - good on Simone for writing it. The fact that the virus emerged in Wuhan are what Alina and her crowd have left PLUS the theories that WIV had SARS-CoV-2 or something very close from *nature* before the pandemic.
  2. 2021-03-08 13:18 Robert F. Garry open
    Billy aka Kevin has written a poem about @Kristian Andersen. He and Nicholson Baker should write something together. [shared file(s): image.png]
  3. 2021-03-08 13:19 Kristian G. Andersen open
    Andrew's tweet is spot on for that exact scenario [shared file(s): Screen Shot 2021-03-08 at 1.18.39 PM.png]
  4. 2021-03-08 13:19 Kristian G. Andersen open
    I like that poem - clever. I should frame it. Thanks Billy.
  5. 2021-03-08 13:27 Edward C. Holmes
    Such great work from Billy. I'm just surprised he can't get financed.
  6. 2021-03-08 13:31 Kristian G. Andersen open
    Maybe he should try selling poetry on Amazon - happy to provide him with material.
  7. 2021-03-08 13:51 Edward C. Holmes open
    Given how cock obsessed Billy is it's not hard to imagine how microscopic his own member must be. I also suspectit requires its own gain of function.
  8. 2021-03-08 14:16 Andrew Rambaut open
    I was going to ask - how hard is it to collect samples with cultureable viruses? From what I am hearing it is difficult toculture SARS-CoV-2 from many samples so I would imagine sampling bats (say) you would be just hoping for RNA rather than infectious virus.
  9. 2021-03-08 14:45 Robert F. Garry open
    Yes - hard to culture from natural samples. First issue is you are getting animals that are likely at different stages ininfections - early, late, persistent, recovering - who knows? We don't know how long viremia lasts in Mastomys with Lassa virus. Seems much lower than in humans. Rabies - long term infections, bats carry for a loooong time eventually some [all?] get sick. For SC2 from humans unless the Ct values are really low say low 20s it's very difficult. Not to say that there is not infectious virus there and that under the right circumstance (inhaling it directly into the nasal passages or lungs even a fairly low may be all it takes. I'm just guessing but unlikely bats would produce their Covs at high levels even if you caught then just right . The intermediate hosts/reservoirs, might grow virus to higher levels (like say civets for SC1), but probably varies a lot from animal to animal like humans . Sicksnotty nose pangolins might have higher loads for their viruses, too. Same apparently true of camels for MERS-CoV. All these considerations are why no-one's cultured ebola virus from a bat yet.

Full conversation →