A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
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Yes, unfortunately - I like her and she's awesome, but there have been several similar instances lately. A lot ofscientists have let SARS-CoV-2 fame go to their head. Too bad, really.We need to get back to the days where Nick was the King of Twitter.
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I don't know her at all, but clearly the fame has gone to her head. She did nothing to change that text. She's learnt all this from Trevor.
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Richard Neher should have done some mentoring as well.
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Hah - you'd imagine him beating the Trevor out of her and replace it with physics smugness :wink:
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2021-03-02 18:01
Edward C. Holmes
Oh, don't get me started...
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Back to science - we just picked up two _very_ interesting "CA" lineage viruses carrying the d144 deletion and a few other mutations, including N501Y and (more intriguingly) L455F - two out of six of the contact residues hit in a single lineage. L455F is rare - mostly seen in a few genomes from Australia. Eddie, do you have any idea if that mutation was looked into? @Robert Garry your eyes on L455F? Remember, the "CA" lineage has the L452R mutation too, so I wonder if those two together might do something funky. [shared file(s): Screen Shot 2021-03-02 at 6.01.56 PM.png, Protein alignment.geneious]
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The screenshot - two bottom sequences = new genomes. Above that, "Type" B.1.429 and above that, Wuhan Hu-1.
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Can you tell me what the Australian sequences are? I'll look into it. No way that L455F will have been studied here.
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I can't... We're unfortunately not allowed to pull GISAID IDs... I can see UK has a few of the double mutants too. https://outbreak.info/situation-reports?pango&muts=S%3AN501Y&muts=S%3AL455F