A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
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Pompeo [shared file(s): China's Reckless Labs Put the World at Risk - WSJ.pdf]
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So much insinuation without actually accusing them of anything
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Hah, this is sooooo terrible. I'm pretty sure that Pompy looked up "Biosafety Level", thought, "That's some scary shit- let's blame China", and grabbed the keyboard.US politicians (and intelligence) actually used to be widely respected in the world. Boy, has that gone downhill.
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2021-02-24 07:44
Kristian G. Andersen
We now have an "NYC" variant... Sigh. Any concerns about any of these mutations - especially the ORF1s? [shared file(s): Screen Shot 2021-02-24 at 7.38.07 AM.png]
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Here's the report on it - rising in NYC (yes, of course there's a preprint...) https://outbreak.info/situation-reports?country=United%20States&division=California[...]20York&pango=B .1.526&selected=New%20York&selectedType=division
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There are 2 subclades of B.1.526 - one has E484K, the other S477N. https://github.com/cov-lineages/pango-designation/issues/6
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Ah, interesting - need to dig a little further then (we can now do pango lineage + mutation on outbreak.info, so that's pretty nifty). If this is the one with, especially, eek, then that's interesting - a lot of standing immunity in large parts ofNYC.
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That's a really good point about all the pre-existing immunity in NYC. E484K doing double duty - ACE2 binding plusa neutralizing epitope. S477N likely the same/overlapping epitope, but NO interaction with ACE2 at least directly. [shared file(s): image.png]